Nolita, sometimes written as NoLIta (North of Little Italy), is a neighborhood in the borough of Manhattan in New York City. Nolita is bounded on the north by Houston Street, on the east by the Bowery, on the south roughly by Broome Street, and on the west by Lafayette Street. It lies east of SoHo, south of NoHo, west of the Lower East Side, and north of Little Italy and Chinatown.

The neighborhood was long regarded as part of Little Italy. The area, however, lost much of its recognizable Italian character in recent decades because of the migration of Italian-Americans out of Manhattan.

In the second half of the 1990s, the neighborhood saw an influx of yuppies and an explosion of expensive retail boutiques and trendy restaurants and bars. After previous unsuccessful tries to pitch the neighborhood as part of SoHo, real estate promoters and others came up with several different names for consideratiion of this newly upscale neighborhood. The name that stuck, as documented in an article on May 5, 1996 in the New York Times City Section debating various monikers for the newly trendy area, was Nolita, an abbreviation for North of Little Italy. This name follows the portmanteau pattern started by SoHo (South of Houston Street), and TriBeCa (Triangle Below Canal Street).

The neighborhood includes St. Patrick's Old Cathedral, at the corner of Mott and Prince Streets, which opened in 1815 and was rebuilt in 1868 after a fire. The cornerstone was laid on June 8, 1809. This building served as New York City's Roman Catholic cathedral until the new St. Patrick's Cathedral was opened on Fifth Avenue in Midtown in 1879. St. Patrick's Old Cathedral is now a parish church.

Another neighborhood landmark is the Puck Building, an ornate structure built in 1885 on the corner of Houston and Lafayette Streets, which originally housed the headquarters of the now-defunct Puck Magazine.

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